If you'd like to use conditional obfuscation at only Release
configuration, we'd recommend to use MSBuild integration provided by Spices.VSIP and embed into your VS Project a simple MSBuild scenario.
How to embed MSBuild into your VS project you can read at Spices.Net Manual (you can see the link to this doc in your Windows Apps menu, at Spices.Net), Spices.Obfuscator\MSBuild Integration chapter.
MSBuild integration provided by Spices.VSIP more flexible than deep VS integration, so you can include additional tasks to your build process and use conditions (like to use Obfuscation task in Release scenario only).
We plan to add conditional obfuscation to the nearest update of Spices.Net, so you'll be able to use conditional obfuscation directly from Spices.VSIP without usage of MSBuild integration of Spices.VSIP.